This scholarship opportunity provides the successful Doctoral candidate with the unique opportunity to visualise the structure and function of the human DNA replication machinery and to receive world-class training in a multidisciplinary research team, led by Dr Jacob Lewis and Dr Lisanne Spenkelink, emerging leaders in cryo-EM and single-molecule imaging of biochemical reactions.
The scholarship is being offered by the University of Wollongong and will contribute to a larger study funded by the ARC. The overall aim of the project is to develop technology to visualise the structure and enzymatic activities of the human replisome, the multiprotein assembly that copies DNA before cell division. A combination of novel single-molecule and state-of-the-art cryo-electron microscopy will be used to define how the human replisome coordinates DNA synthesis during times of replication stress.
The recruited researcher will benefit from access to cutting-edge biochemistry, single-molecule fluorescence, and electron microscopy infrastructure at Molecular Horizons. The scholar will gain skills in protein biochemistry, single-molecule imaging, and cryo-EM sample preparation and big-data processing. Our team has a strong track record of publishing high-impact biomedical research.
Faculty: Faculty of Science, Medicine and Health
Study area: Physics
Student type: Domestic students, International students
Student status: Current student, Future Students
Scholarship amount
Sucessful candidates will recieve a tax free stipend of $34,000 p.a for the duration of the award.
Duration
3.5 years.
Application process
Please format the application as a single PDF document that includes a cover letter outlining relevant experience (1 page max), a Curriculum Vitae, a copy of academic transcript, and contact details for 2 academic referees.
- Please submit applications to Dr Jacob Lewis (jacobl@uow.edu.au) or Dr Lisanne Spenkelink (lisanne@uow.edu.au) .
Eligibility requirements
Applicants should hold an Honours 1 or high 2A (or equivalent) undergraduate degree in a relevant discipline or the equivalent combination of professional experience and academic qualifications. Experience in wet-lab laboratory techniques is essential, a background in biochemistry and cryo-EM would be highly desirable.
Application closing date
Sunday 30 June 2024