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Cryo-Electron Microscopy

Publications

Authorship

  • Hills, Francesca R., Alice-Roza Eruera, James Hodgkinson-Bean, Fátima Jorge, Richard Easingwood, Simon HJ Brown, James C. Bouwer, Yi-Ping Li, Laura N. Burga, and Mihnea Bostina. "Variation in structural motifs within SARS-related coronavirus spike proteins." PLoS Pathogens 20, no. 5 (2024): e1012158.
  • Brown, Simon HJ, James C. Bouwer, and Scott B. Cohen. "Highly amine-reactive graphene-oxide EM grids for biochemical surface modification in aqueous buffer." bioRxiv (2023): 2023-11.
  • Zeng, Yi C., Meghna Sobti, Ada Quinn, Nicola J. Smith, Simon HJ Brown, Jamie I. Vandenberg, Renae M. Ryan, Megan L. O’Mara, and Alastair G. Stewart. "Structural basis of promiscuous substrate transport by Organic Cation Transporter 1." Nature communications 14, no. 1 (2023): 6374.
  • Rouet, Romain, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Brown, Simon, et al. "Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients." Nature communications 14, no. 1 (2023): 687.
  • Sobti, Meghna, Yi C. Zeng, James L. Walshe, Simon HJ Brown, Robert Ishmukhametov, and Alastair G. Stewart. "Changes within the central stalk of E. coli F1Fo ATP synthase observed after addition of ATP." Nature Communications Biology 6, no. 1 (2023): 26.
  • Newing, Timothy P., Jodi L. Brewster, Lucy J. Fitschen, James C. Bouwer, Nikolas P. Johnston, Haibo Yu, and Gökhan Tolun. "Redβ177 annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination." Nature communications 13, no. 1 (2022): 1-14.
  • Wang, Zhijie, Yanyan Wang, Baohua Li, James C. Bouwer, Kenneth Davey, Jun Lu, and Zaiping Guo. Non‐Flammable Ester Electrolyte with Boosted Stability Against Li for High‐Performance Li metal Batteries. Angewandte Chemie International Edition (2022).
  • Bishnu P Paudel, Zhi-Qiang Xu, Slobodan Jergic, Aaron J Oakley, Nischal Sharma, Simon HJ Brown, James C Bouwer, Peter J Lewis, Nicholas E Dixon, Antoine M vanOijen, and Harshad Ghodke, Mechanism of transcription modulation by the transcription-repair coupling factor, Nucleic Acids Research (2022): 1-24
  • Chou, Shulei, Florian Gebert, David L. Cortie, James C. Bouwer, Wanlin Wang, Zichao Yan, and Shi-Xue Dou. Epitaxial Nickel Ferrocyanide Stabilizes Jahn‐Teller Distortions of Manganese Ferrocyanide for Sodium‐Ion Batteries. Angewandte Chemie (2021).
  • Newing, Timothy P., Aaron J. Oakley, Michael Miller, Catherine J. Dawson, Simon HJ Brown, James C. Bouwer, Gökhan Tolun, and Peter J. Lewis. Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD. Nature Communications 11, no. 1 (2020): 1-11.
  • Meghna Sobti, Robert Ishmukhametov, James C Bouwer, Anita Ayer, Cacang Suarna, Nicola J Smith, Mary Christie, Roland Stocker, Thomas M Duncan, Alastair G Stewart; Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP. eLife (2019); 8:e43864 DOI: 10.7554/eLife.43864.
  • Sobti, Meghna, Hiroshi Ueno, Simon HJ Brown, Hiroyuki Noji, and Alastair G. Stewart. "The series of conformational states adopted by rotorless F1-ATPase during its hydrolysis cycle." Structure 32, no. 4 (2024): 393-399.
  • Rouet, Romain, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Simon Brown, et al. "Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients." Nature communications 14, no. 1 (2023): 687.
  • Zeng YC, Sobti M, Quinn A, Smith NJ, Brown SHJ, Vandenberg JI, Ryan RM, O’Mara ML, and Stewart AG (2023) Structural Basis of Promiscuous Substrate Transport in Organic Cation Transporter. Nature Communications Accepted 19 September 2023
  • Sobti, Meghna, Yi C. Zeng, James L. Walshe, Simon HJ Brown, Robert Ishmukhametov, and Alastair G. Stewart. "Changes within the central stalk of E. coli F1Fo ATP synthase observed after addition of ATP." Nature Communications Biology 6, no. 1 (2023): 26.
  • Newing, Timothy P., Jodi L. Brewster, Lucy J. Fitschen, James C. Bouwer, Nikolas P. Johnston, Haibo Yu, and Gökhan Tolun. "Redβ177 annealase structure reveals details of oligomerization and λ Red-mediated homologous DNA recombination." Nature communications 13, no. 1 (2022): 1-14.
  • Wang, Zhijie, Yanyan Wang, Baohua Li, James C. Bouwer, Kenneth Davey, Jun Lu, and Zaiping Guo. Non‐Flammable Ester Electrolyte with Boosted Stability Against Li for High‐Performance Li metal Batteries. Angewandte Chemie International Edition (2022).
  • Bishnu P Paudel, Zhi-Qiang Xu, Slobodan Jergic, Aaron J Oakley, Nischal Sharma, Simon HJ Brown, James C Bouwer, Peter J Lewis, Nicholas E Dixon, Antoine M vanOijen, and Harshad Ghodke, Mechanism of transcription modulation by the transcription-repair coupling factor, Nucleic Acids Research (2022): 1-24
  • Chou, Shulei, Florian Gebert, David L. Cortie, James C. Bouwer, Wanlin Wang, Zichao Yan, and Shi-Xue Dou. Epitaxial Nickel Ferrocyanide Stabilizes Jahn‐Teller Distortions of Manganese Ferrocyanide for Sodium‐Ion Batteries. Angewandte Chemie (2021).
  • Newing, Timothy P., Aaron J. Oakley, Michael Miller, Catherine J. Dawson, Simon HJ Brown, James C. Bouwer, Gökhan Tolun, and Peter J. Lewis. Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD. Nature Communications 11, no. 1 (2020): 1-11.
  • Meghna Sobti, Robert Ishmukhametov, James C Bouwer, Anita Ayer, Cacang Suarna, Nicola J Smith, Mary Christie, Roland Stocker, Thomas M Duncan, Alastair G Stewart; Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP. eLife (2019); 8:e43864 DOI: 10.7554/eLife.43864.

Acknowledgements

  • Sobti, Meghna, Hiroshi Ueno, Hiroyuki Noji, and Alastair G. Stewart. The six steps of the complete F1-ATPase rotary catalytic cycle. Nature Communications 12, no. 1 (2021): 1-10.