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Clinical/Disease States

Clinical/Disease States

Grant Successes

  1. Obesity
  2. Diabetes

    Atherogenicity of Intermediate Density Lipoproteins in people with and without type 2 diabetes mellitus. DART 2005 (Meyer, Jessup) $44K.

    Dilinoleoyl phosphatidic acid as a novel mediator of insulin resistance in muscle. NHMRC 2008-10 (Schmitz-Peiffer, Mitchell) $483K.

  3. Cardiovascular Disease
    Development and evaluation of novel foods enriched with very long chain omega-3 fatty acids. ARC Linkage 2002/5 (Howe, Mori, Tapsell, Meyer), $283K.

    Development and nutritional evaluation of novel soy based foods. ARC Linkage 2003/6 (Meyer, Howe, Mori) ARC Linkage grant. $287K.

    Long Chain Omega-3 Polyunsaturated Fatty Acids and Heart Health in Humans. ARC APA-I 2006/9 (Meyer, Sinclair, Gibson) $78K.

    ASPREE Study (currently NIH Funded) ? will submit to NHMRC as a sub-study to assess omega-3 status.

  4. Depression/Schizophrenia

    Fish Oil in the treatment of major depression. Clover Corporation 2002/3 (Grenyer, Crowe, Howe, Meyer, Owen) $50K.

  5. Post-natal depression
    Randomised trial of DHA in pregnancy to prevent postnatal depressive symptoms and enhance neurodevelopment in children. NHMRC 2005/9 (Makrides, et al Else, Meyer) $1,644K.

  6. Children with ADHD

  7. Cataract/presbiopia/dry eye

    Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye. ARC linkage 2009-11 (Blanksby, Mitchell, Willcox, Zhao) 395K.

  8. Stress

    A randomised controlled trial of EPA-rich fish oil in Chronic Stress. NHMRC 2009/10/11 (Myers, Sinclair, Stough, Meyer, Leach, Brooks + AIs)  $206K.

Publications

  1. Obesity

  2. Diabetes

    Yvonne Cheung still doing corrections on her thesis ? publications to come.

    Brown MA, Storlien LH, Huang XF, Tapsell LC, Else PL, Higgins JA, Brown IL (2009) Dietary Fat and Carbohydrate Composition: Metabolic Disease, Chapter 21 In: Fat Detection:Taste, Texture and Post Ingestion Effects. (Ed Montmayeur J-P & le Coutre S). Taylor and Francis, London UK (in press 2/1/09).

    Turner N, Mitchell TW, Else PL, Hulbert AJ (2009) Omega-3 and omega-6 fats in meals: A proposal for a simple new label. Asian Pacific Journal of Clinical Nutrition (revised manuscript submitted).

    Hulbert AJ, N Turner, LH Storlien & PL Else (2005) Dietary fats and membrane function: implications for metabolism and disease. Biological Reviews 80:155-169.

  3. Cardiovascular Disease

    Meyer BJ, Duvillard L, Owen AJ, Packard CJ, Caslake MJ Fractionation of cholesteryl ester rich intermediate density lipoprotein subpopulations by chondroitin sulphate. Atherosclerosis 2007 Dec 195(2):e28-34 Epub 2007 Mar 6.

    Meyer BJ, Hammervold T, Rustan ACHr, Howe PRC. Dose Dependent Effects of DHA Supplementation in Statin Treated Hyperlipidaemic Subjects Lipids 2007;42(2):109-115.

    Murphy K, Meyer BJ, Mori TA, Mori TA, Burke V, Mansour J, Patch CS, Tapsell LC, Noakes M, Clifton PA, Barden A, Puddey IB, Beilin LJ, Howe PRC. Impact of foods enriched with omega-3 long chain polyunsaturated fatty acids on erythrocyte omega-3 levels and cardiovascular risk factors. British Journal of Nutrition 2007;97:749-757.

    Patch CS, Tapsell LC, Mori TA, Meyer BJ, Murphy KJ, Mansour J, Noakes M, Clifton PA, Puddey IB, Beilin LJ, Annison G, Howe PRC. The use of novel foods enriched with long chain omega-3 fatty acids to increase dietary intake: A comparison of methodologies assessing nutrient intake. Journal of American Dietetic Association. 2005 Dec 105(12):1918-1926.

  4. Depression/Schizophrenia

    Grenyer BFS, Crowe T, Meyer B, Owen AJ, Grigonis-Deane EM, Caputi P, Howe PRC. Fish oil supplementation in the treatment of major depression: A randomised double-blind placebo-controlled trial. Progress in Neuro-Psychopharmacology & Biological Psychiatry 2007;31:1393-1396.

    Monterrubio S, Solowij N, Meyer B, Turner N. Fatty acid relationships in former cannabis users with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry, 2006 Mar;30(2):280-285.

  5. Post-natal depression

    Trial still going, therefore no publications yet.

  6. Children with ADHD

    Ng K-H, Meyer BJ, Reece L, Sinn N. Dietary polyunsaturated fatty acid intakes in children with ADHD symptoms. British Journal of Nutrition 2009 (accepted).

  7. Cataract/presbiopia/dry eye

    Saville JT, Zhao Z, Willcox MDP, Mitchell TW and Blanksby SJ. The effect of contact lens material and lens care solutions on the in vivo deposition of polar and non-polar tear lipids. Investigative Ophthalmology and Vision Science 2009; (Submitted for review).

    Deeley JM, Hankin JA, Friedrich MG, Murphy RC, Truscott RJW, Blanksby SJ and Mitchell TW. Sphingolipid distribution changes with age in the human lens. Journal of Lipid Research 2009; (Submitted for review).

  8. Stress

    The research project will commence July 2009 ? hence no publications yet.